High-dose Insulin Euglycemic Therapy (HIET)

Twistadmin Poison Alerts

High-dose Insulin Euglycemic Therapy (HIET) is an advanced first-line treatment for life-threatening Calcium Channel Blocker (CCB) overdose. Its use has also proven efficacious in severe Beta Blocker (BB) poisoning, as well as combined exposure to both agents. HIET restores cardiac output and ameliorates associated symptoms while conventional therapies such as …

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Perplexing Paresthesias

Twistadmin Poison Alerts

PERPLEXING PARESTHESIAS – Could Your Patient Have a Pyrethroid Insecticide Exposure? The National Pesticide Information Center (NPIC), a cooperative effort between Oregon State University and the EPA, has noted that over the past ten years, there have been some significant changes in the types of insecticides that have been seen …

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Molly Are These Your Bath Salts?

Twistadmin Poison Alerts

Drug abuse with synthetic substances is not a new phenomenon, but it is interesting and can be challenging to health care providers.  Patterns of abuse and the types of drugs being abused changes over time.  There has been a dramatic increase in the use of synthetic drugs, including bath salts, …

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Button Batteries

Twistadmin Poison Alerts

The least considered… As the seasons turn so do the types of calls the Missouri Poison Center receives on the hotline.  From summer stings and sunscreen we now turn our attention to the winter’s mix of cold medicines, antifreeze, and one substance that often is not thought to be much …

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Buprenorphine

Twistadmin Poison Alerts

Buprenorphine, typically in combination with naloxone (e.g., Suboxone®), is prescribed to treat opioid addiction.  Buprenorphine alone may also be prescribed for pain management and opioid addiction. It has the potential to cause delayed and persistent CNS and respiratory depression for up to 24 hours following ingestion.  How does buprenorphine differ …

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Aspirin Overdose Remains a Concern

Twistadmin Poison Alerts

The use of aspirin as a pain reliever and antipyretic has declined over the years with the increased use of acetaminophen and NSAIDs and the historical association of aspirin and Reye’s Syndrome in children. The discovery, however, that aspirin can decrease the incidence of coronary artery disease has led to …

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