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Package Of Xylazine

Be Aware of Xylazine-Adulterated Fentanyl

You give naloxone – a lot of naloxone – and the patient still has some CNS and respiratory depression and hypotension. What gives? Fentanyl has almost replaced heroin in recreational drugs, but the creators of such experiences are always trying…

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A Box Of Generic Gabapentin Pills.


Gabapentin (Neurontin®, others) is FDA-approved for partial-onset seizures, post-herpetic neuralgia, and restless leg syndrome; pregabalin (Lyrica®) for fibromyalgia, various painful neuralgias, and partial-onset seizures. Both have myriad off-label uses including chronic cough, migraine prophylaxis, pruritus, bipolar and anxiety disorders, hot…

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An Image Of Long Pills On A Reflective Blue Table.


Since its introduction in 1995, tramadol has become the second most-widely-prescribed opioid analgesic in the US, topped only by combination hydrocodone-acetaminophen. It is most effectively used for chronic, moderate-to-severe pain conditions such as neuropathic pain and osteoarthritis, but it also…

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POISON ALERT: Sulfonylurea Overdose Treatment

Often included in “One Pill Can Kill” lists, sulfonylureas (SU) have the potential for significant toxicity in overdose. These medications were the first orally-active agents to treat Type 2 Diabetes, approved in the late 1950s, but now represent only one class among many newer antidiabetic agents and combination products.
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