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Poison Alerts

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Be Aware of Xylazine-Adulterated Fentanyl

You give naloxone – a lot of naloxone – and the patient still has some CNS and respiratory depression and hypotension. What gives? Fentanyl has almost replaced heroin in recreational drugs, but the creators of such experiences are always trying to improve the high, and perhaps the profits, by including additional ingredients. Xylazine is an up-and-coming tag-along with fentanyl that is causing clinically-significant toxicity. Xylazine-adulterated fentanyl has made its way to the Midwest.  What is xylazine? Xylazine is a non-opioid veterinary procedural sedative with anesthetic and muscle relaxant properties. It is a centrally-acting alpha-2 adrenergic agonist, similar to the sedative…

Antidote Chart

Click the button below to download the most recent version of the Missouri Poison Center’s Antidote Chart.

Revised in 2021

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Professional Education

Professional education is a priority at the Missouri Poison Center. The center offers various educational programs for licensed health care providers, medical residents, fellows in training, and students from multiple medical disciplines. Our professional staff provides programs on-site, at universities, and in health care facilities throughout Missouri.

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Pharmacy Education

The Missouri Poison Center serves as a training site for Advanced Pharmacy Practice Experience (APPE). This on-site five-week rotation allows the student the opportunity to learn basic clinical toxicology principles and experience the operations of the poison center. This dynamic and interactive rotation is under the guidance of a toxicologist and poison specialists.

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EMS/First Responder Training

EMS providers need to know when to call the poison center. Often, such a call can save lives, prevent unnecessary emergency department visits, and fast-track treatment. Learn which toxic situations warrant a call to the Missouri Poison Center. Click here to learn more.

For more poison information or to schedule a program, contact our Community Outreach Coordinator at 1-866-612-5719.

  • Poison specialists help hospitals care for their poisoned patients by providing optimal care and serving as a safety net for risk management.
  • Our team follows patients through their hospital stay and continues to make treatment recommendations as necessary.
  • Patients managed with poison center expertise experience shorter hospitalizations, which helps health care providers improve the quality of care and decrease overall health care costs.


All calls to the Missouri Poison Center are confidential. Patient information is protected in compliance with HIPAA regulations, with poison centers recognized specifically recognized within the privacy rule.

Take The Missouri Poison Center With You

Emergencies don’t wait for you, so you shouldn’t have to wait to call for help. Get the Missouri Poison Center app with poison information and a link to the Poison Help Line. It is just a click away during the most stressful moments. Our registered nurses and pharmacists are here 24/7/365 days a year to help guide you through poison exposures and overdose emergencies.

Don’t wait. Download now.

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