METFORMIN DOESN’T LOWER BLOOD SUGAR IN DOSING MISHAPS OVERDOSE
This statement might come as a surprise to many people who take metformin to control blood sugar. Of course, over time, metformin lowers a patient’s blood sugar, but that’s usually not what we are watching for when we receive calls about this medicine. The Missouri Poison Center has taken hundreds of calls about dosing mistakes and even children getting into metformin. The fact remains, metformin doesn’t cause a rapid drop in blood sugar in these cases, because it just doesn’t affect the body in that way. Metformin decreases the absorption of glucose (sugar) from food in the intestines, lowers the amount of glucose (sugar) made by the liver, and it also helps insulin work better in the tissues of our body. Notice, it works more indirectly to lower blood sugar and does not directly increase the release of insulin. So, what symptoms might occur after accidental poisonings or dosing mistakes? Common symptoms include upset stomach, vomiting, gas, and diarrhea. Larger overdoses and/or taking the medicine with significant kidney disease can cause serious symptoms such as lactic acidosis.